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Comparative analysis of retinal photoplethysmographic spatial maps and thickness of retinal nerve fiber layer.


ABSTRACT: The paper presents a comparative study of the pulsatile attenuation amplitude (PAA) within the optic nerve head (ONH) at four different areas calculated from retinal video sequences and its relevance to the retinal nerve fiber layer thickness (RNFL) changes in normal subjects and patients with different stages of glaucoma. The proposed methodology utilizes processing of retinal video sequences acquired by a novel video ophthalmoscope. The PAA parameter measures the amplitude of heartbeat-modulated light attenuation in retinal tissue. Correlation analysis between PAA and RNFL is performed in vessel-free locations of the peripapillary region with the proposed evaluating patterns: 360° circular area, temporal semi-circle, nasal semi-circle. For comparison, the full ONH area is also included.

SUBMITTER: Odstrcilik J 

PROVIDER: S-EPMC10162550 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature