Spike-phase coupling patterns reveal laminar identity in primate cortex.

ABSTRACT: The cortical column is one of the fundamental computational circuits in the brain. In order to understand the role neurons in different layers of this circuit play in cortical function it is necessary to identify the boundaries that separate the laminar compartments. While histological approaches can reveal ground truth they are not a practical means of identifying cortical layers in vivo. The gold standard for identifying laminar compartments in electrophysiological recordings is current-source density (CSD) analysis. However, laminar CSD analysis requires averaging across reliably evoked responses that target the input layer in cortex, which may be difficult to generate in less well-studied cortical regions. Further, the analysis can be susceptible to noise on individual channels resulti

SUBMITTER: Davis ZW 

PROVIDER: S-EPMC10162800 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature