Comprehensive Review of Methods to Assess Uncertainty in Health Economic Evaluations.

ABSTRACT: Uncertainty assessment is a cornerstone in model-based health economic evaluations (HEEs) that inform reimbursement decisions. No comprehensive overview of available uncertainty assessment methods currently exists. We aimed to review methods for uncertainty assessment for use in model-based HEEs, by conducting a snowballing review. We categorised all methods according to their stage of use relating to uncertainty assessment (identification, analysis, communication). Additionally, we classified identification methods according to sources of uncertainty, and subdivided analysis and communication methods according to their purpose. The review identified a total of 80 uncertainty methods: 30 identification, 28 analysis, and 22 communication methods. Uncertainty identification methods exist to

SUBMITTER: Otten TM 

PROVIDER: S-EPMC10163110 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature