Effects of qCON and qNOX-guided general anaesthesia management on patient opioid use and prognosis: a study protocol.

ABSTRACT:

Introduction

The adverse effects of general anaesthetic drugs (especially opioids) cannot be ignored. However, current nociceptive-monitoring techniques still lack consistency in guiding the use of opioids. This trial will study the demand for opioid use and patient prognosis in qCON and qNOX-guided general anaesthesia management.

Methods and analysis

This prospective, randomised, controlled trial will randomly recruit 124 patients undergoing general anaesthesia for non-cardiac surgery in equal numbers to either the qCON or BIS group. The qCON group will adjust intraoperative propofol and remifentanil dosage according to qCON and qNOX values, while the BIS group will adjust according to BIS values and haemodynamic fluctuations. The differences between the two groups will be

SUBMITTER: Kang J 

PROVIDER: S-EPMC10163456 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature