Assessing the potential cost-effectiveness of centralised versus point-of-care testing for hepatitis C virus in Pakistan: a model-based comparison.

ABSTRACT:

Objectives

Pakistan has a hepatitis C virus (HCV) infection prevalence of 6%-9% and aims to achieve World Health Organisation (WHO) targets for elimination of HCV by the year 2030. We aim to evaluate the potential cost-effectiveness of a reference laboratory-based (centralised laboratory testing; CEN) confirmatory testing approach versus a molecular near-patient point-of-care (POC) confirmatory approach to screen the general population for HCV in Pakistan.

Study design

We used a decision tree-analytic model from a governmental (formal healthcare sector) perspective.

Study setting

Individuals were assumed to be initially screened with an anti-HCV test at home, followed by POC nucleic acid test (NAT) at nearby district hospitals or followed by NAT at centralised laborat

SUBMITTER: Babigumira JB 

PROVIDER: S-EPMC10163545 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature