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Cross-cultural validity of the Pulmonary Embolism Quality of Life questionnaire in the quality of life survey after pulmonary embolism: A Persian-speaking cohort.


ABSTRACT:

Background

The Pulmonary Embolism Quality of Life (PEmb-QoL) questionnaire is the first disease-specific scale for assessing the quality of life in patients with a history of pulmonary embolism (PE).

Objectives

To assess the cross-cultural validity and reliability of the disease-specific PEmb-QoL questionnaire.

Methods

The Persian version was prepared through the forward and backward translation of the English questionnaire. Six months after the diagnosis of acute PE, consecutive Persian-speaking patients were asked to complete the PEmb-QoL, the generic 36-item Short Form (SF-36) questionnaires and undertake a 6-minute walk test (6MWT). Acceptability was assessed via item missing rate, reproducibility by the test-retest method, and internal consistency reliability by Cronbach's α and McDonald's ω coefficients. Convergence validity was assessed using the Spearman rank correlation between scores of PEmb-QoL, SF-36, and 6MWT. The questionnaire structure was evaluated through exploratory factor analysis.

Results

Ninety-six patients with a confirmed diagnosis of PE completed the questionnaires. The Persian version of PEmb-QoL had good internal consistency (α = 0.95, 3-factor ω = 0.96), inter-item correlation (0.3-0.62), item-total correlation (0.38-0.71), reproducibility (test-retest ICC with 25 participants = 0.92-0.99), and good discriminant validity. Convergence validity was confirmed by the moderate-to-high correlations between PEmb-QoL and SF-36 scores, and a good correlation between the "limitation in daily activities" dimension of the PEmb-QoL questionnaire and 6MWT results. Exploratory factor analysis suggested a 3-component structure with functional (items 1h, 4b-5d, 6, 8, 9i, and 9j), symptoms (1b-h, 7, and 8), and emotional (5a, 6, and 9a-h) components.

Conclusion

The Persian version of the PEmb-QoL questionnaire is valid and reliable for measuring the disease-specific quality of life in patients with PE.

SUBMITTER: Mehdizadeh K 

PROVIDER: S-EPMC10163673 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature

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Publications

Cross-cultural validity of the Pulmonary Embolism Quality of Life questionnaire in the quality of life survey after pulmonary embolism: A Persian-speaking cohort.

Mehdizadeh Kasra K   Salehi Maryam Mohseni MM   Moosavi Jamal J   Mohebbi Bahram B   Klok Frederikus A FA   Bikdeli Behnood B   Shafe Omid O   Pouraliakbar Hamidreza H   Alizadehasl Azin A   Farrashi Melody M   Kaviani Raheleh R   Mehrvarz Farzaneh F   Rashidi Farid F   Talakoob Hamed H   Bakhshandeh Hooman H   Sadeghipour Parham P  

Research and practice in thrombosis and haemostasis 20230301 3


<h4>Background</h4>The Pulmonary Embolism Quality of Life (PEmb-QoL) questionnaire is the first disease-specific scale for assessing the quality of life in patients with a history of pulmonary embolism (PE).<h4>Objectives</h4>To assess the cross-cultural validity and reliability of the disease-specific PEmb-QoL questionnaire.<h4>Methods</h4>The Persian version was prepared through the forward and backward translation of the English questionnaire. Six months after the diagnosis of acute PE, conse  ...[more]

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