Cross-national harmonization of neurocognitive assessment across five sites in a global study.

ABSTRACT:

Objective

Cross-national work on neurocognitive testing has been characterized by inconsistent findings, suggesting the need for improved harmonization. Here, we describe a prospective harmonization approach in an ongoing global collaborative study.

Method

Visuospatial N-Back, Tower of London (ToL), Stop Signal task (SST), Risk Aversion (RA), and Intertemporal Choice (ITC) tasks were administered to 221 individuals from Brazil, India, the Netherlands, South Africa, and the USA. Prospective harmonization methods were employed to ensure procedural similarity of task implementation and processing of derived task measures across sites. Generalized linear models tested for between-site differences controlling for sex, age, education, and socioeconomic status (SES). Associa

SUBMITTER: Batistuzzo MC 

PROVIDER: S-EPMC10164281 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature