Project description:In this work we describe a robust fosfomycin collateral sensitivity phenotype of Pseudomonas aeruginosa resistant mutants selected by antibiotics from different structural families. The underlying mechanism was the reduced expression of the genes encoding the peptidoglycan-recycling pathway, which preserves the peptidoglycan synthesis in situations where the de novo synthesis is blocked, and of fosA, encoding a fosfomycin-inactivating enzyme.

2022-03-02 | GSE153006 | GEO

Iron and Pseudomonas aeruginosa biofilm formation.

Project description: Not available

| S-EPMC1182440 | biostudies-literature

Evaluation of GeneXpert PA assay compared to genomic and (semi-)quantitative culture methods for direct detection of Pseudomonas aeruginosa in endotracheal aspirates.

Project description: Not available

| S-EPMC8300976 | biostudies-literature

ROS-based lethality of Caenorhabditis elegans mitochondrial electron transport mutants grown on Escherichia coli siderophore iron release mutants.

Project description: Not available

| S-EPMC6815122 | biostudies-literature

Collateral Sensitivity to Fosfomycin of Tobramycin-Resistant Mutants of Pseudomonas aeruginosa Is Contingent on Bacterial Genomic Background.

Project description: Not available

| S-EPMC10138353 | biostudies-literature

Bispecific Thio-Linked Disaccharides as Inhibitors of Pseudomonas Aeruginosa Lectins LecA (PA-IL) and LecB (PA-IIL): Dual-Targeting Strategy.

Project description: Not available

| S-EPMC11753388 | biostudies-literature

Ferrous iron sensing in Pseudomonas aeruginosa

Project description:To determine whether P. aeruginosa strain PA14 exhibits a specific transcriptional response to extracellular Fe(II), a microarray experiment was performed using Affymetrix GeneChips. The transcriptional response to Fe(II) or Fe(III) shock was measured and compared to a no-Fe control.

2012-02-29 | E-MEXP-3459 | biostudies-arrayexpress

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