Clomiphene citrate: A potential alternative for testosterone therapy in hypogonadal males.

ABSTRACT:

Background

Hypogonadism is a worldwide problem among men causing sexual, physical and mental problems. Testosterone therapy is the first-choice treatment for male hypogonadism, with several side effects, that is, subfertility. Clomiphene citrate (CC) is an alternative off-label therapy for a certain group of hypogonadal males, especially for those with an active or future child wish. There is scarce literature in usage of CC for men with hypogonadism. The aim of this retrospective study was to evaluate the effectiveness and safety of CC for hypogonadal males.

Methods

In this single-centre study, men treated with CC for hypogonadism were evaluated retrospectively. Primary outcome was hormonal evaluation including total testosterone (TT), free testosterone (FT), luteinizing ho

SUBMITTER: Huijben M 

PROVIDER: S-EPMC10164424 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature