Interferential therapy for chronic constipation in adults: The CON-COUR randomizedcontrolled trial.

ABSTRACT:

Background

Chronic constipation (CC) is a frequent condition, and the first-line treatment includes dietary rules, the use of laxatives, and biofeedback for evacuation disorders. However, almost half of the patients are dissatisfied with their current treatment. We report the first double-blind randomized multicenter trial assessing the effectiveness of transabdominal electrical stimulation by interferential therapy (IFT) in the treatment of CC in adults.

Methods

A prospective, multicenter, randomized, double-blind, sham-controlled, parallel-group, phase 3 trial was conducted at 7 centers in France. The primary endpoint was 8-week efficacy as defined by the number of complete spontaneous bowel movements during the last 4 weeks of the 8-week stimulation period. Secondary endp

SUBMITTER: Vitton V 

PROVIDER: S-EPMC10165323 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature