Coronary artery disease and revascularization associated with immune checkpoint blocker myocarditis: Report from an international registry.

ABSTRACT:

Purpose

Immune checkpoint blocker (ICB) associated myocarditis (ICB-myocarditis) may present similarly and/or overlap with other cardiac pathology including acute coronary syndrome presenting a challenge for prompt clinical diagnosis.

Methods

An international registry was used to retrospectively identify cases of ICB-myocarditis. Presence of coronary artery disease (CAD) was defined as coronary artery stenosis >70% in patients undergoing coronary angiogram.

Results

Among 261 patients with clinically suspected ICB-myocarditis who underwent a coronary angiography, CAD was present in 59/261 patients (22.6%). Coronary revascularization was performed during the index hospitalisation in 19/59 (32.2%) patients. Patients undergoing coronary revascularization less frequently r

SUBMITTER: Nowatzke J 

PROVIDER: S-EPMC10165738 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature