Flow cytometry profiling of cellular immune response in COVID-19 infected, recovered and vaccinated individuals.

ABSTRACT:

Introduction

SARS-CoV-2 has infected over 753 million individuals and caused more than 6.8 million deaths globally to date. COVID-19 disease severity has been associated with SARS-CoV-2 induced hyper inflammation and the immune correlation with its pathogenesis remains unclear. Acute viral infection is characterised by vigorous coordinated innate and adaptive activation, including an early cellular response that correlates well with the amplitude of virus specific humoral response.

Objective

The present study covers a wide spectrum of cellular immune response against COVID-19, irrespective of infection and vaccination.

Methods

We analysed immune status of (a) COVID-19 hospitalised patients including deceased and recovered patients, and compared with home isolated and

SUBMITTER: Kumari D 

PROVIDER: S-EPMC10165874 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature