Proton Therapy for Bilateral Breast Cancer Maximizes Normal-Tissue Sparing.

ABSTRACT:

Purpose

Treatment for bilateral breast cancer with radiation therapy is technically challenging. We evaluated the clinical and dosimetric outcomes of a small series of patients with synchronous bilateral breast cancer, including a photon dosimetric comparison, to identify optimal treatment planning approaches.

Materials and methods

We reviewed a registry of patients (simultaneously) diagnosed with synchronous bilateral breast cancers who underwent postoperative definitive adjuvant proton therapy at our institution between 2012 and 2021. All patients were treated with double-scattered proton or pencil-beam scanning therapies. For comparison, intensity-modulated radiation therapy photon plans optimized for organ sparing and coverage were generated after treatment.

Results</

SUBMITTER: Brooks ED 

PROVIDER: S-EPMC10166012 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature