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Management of B-cell lineage acute lymphoblastic leukemia: expert opinion from an Indian panel via Delphi consensus method.


ABSTRACT:

Introduction

Currently, there are no guidelines for the management of B-cell lineage acute lymphoblastic leukemia (B-ALL) from an Indian perspective. The diagnostic workup, monitoring, and treatment of B-ALL vary among different physicians and institutes.

Objective

To develop evidence-based practical consensus recommendations for the management of B-ALL in Indian settings.

Methods

Modified Delphi consensus methodology was considered to arrive at a consensus. An expert scientific committee of 15 experts from India constituted the panel. Clinically relevant questions belonging to three major domains were drafted for presentation and discussion: (i) diagnosis and risk assignment; (ii) frontline treatment; and (iii) choice of therapy (optimal vs. real-world practice) in r

SUBMITTER: Mathews V 

PROVIDER: S-EPMC10166232 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature