Causes of death among early-onset colorectal cancer population in the United States: a large population-based study.

ABSTRACT:

Background

Early-onset colorectal cancer (EOCRC) has an alarmingly increasing trend and arouses increasing attention. Causes of death in EOCRC population remain unclear.

Methods

Data of EOCRC patients (1975-2018) were extracted from the Surveillance, Epidemiology, and End Results database. Distribution of death was calculated, and death risk of each cause was compared with the general population by calculating standard mortality ratios (SMRs) at different follow-up time. Univariate and multivariate Cox regression models were utilized to identify independent prognostic factors for overall survival (OS).

Results

The study included 36,013 patients, among whom 9,998 (27.7%) patients died of colorectal cancer (CRC) and 6,305 (17.5%) patients died of non-CRC causes. CRC dea

SUBMITTER: Chen Y 

PROVIDER: S-EPMC10166590 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature