COVID-19 Therapeutics: An Update on Effective Treatments Against Infection With SARS-CoV-2 Variants.

ABSTRACT: The coronavirus disease 2019 (COVID-19) pandemic is one of the most consequential global health crises in over a century. Since its discovery in 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to mutate into different variants and sublineages, rendering previously potent treatments and vaccines ineffective. With significant strides in clinical and pharmaceutical research, different therapeutic strategies continue to be developed. The currently available treatments can be broadly classified based on their potential targets and molecular mechanisms. Antiviral agents function by disrupting different stages of SARS-CoV-2 infection, while immune-based treatments mainly act on the human inflammatory response responsible for disease severity. In this review, we discus

SUBMITTER: Padasas BT 

PROVIDER: S-EPMC10166656 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature