The role of substance use disorders in the transition from suicide attempt to suicide death: a record linkage study of a Swedish cohort.

ABSTRACT:

Background

Suicidal behavior and substance use disorders (SUDs) are important public health concerns. Prior suicide attempts and SUDs are two of the most consistent predictors of suicide death, and clarifying the role of SUDs in the transition from suicide attempt to suicide death could inform prevention efforts.

Methods

We used national Swedish registry data to identify individuals born 1960-1985, with an index suicide attempt in 1997-2017 (N = 74 873; 46.7% female). We assessed risk of suicide death as a function of registration for a range of individual SUDs. We further examined whether the impact of SUDs varied as a function of (i) aggregate genetic liability to suicidal behavior, or (ii) age at index suicide attempt.

Results

In univariate models, risk of s

SUBMITTER: Edwards AC 

PROVIDER: S-EPMC10166763 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature