Immune-enhancing activity of polysaccharides and flavonoids derived from Phellinus igniarius YASH1.

ABSTRACT: Introduction: Phellinus igniarius (P. igniarius) (Sanghuang) is a widely used traditional Chinese medicine fungus, and its natural products have great potential for clinical application in immune enhancement. This study aimed to explore the immune-enhancing activity and underlying mechanisms of the polysaccharides and flavonoids derived from Phellinus igniarius (P. igniarius) and to provide a theoretical and experimental basis for the development of novel drugs. Methods: Wild P. igniarius YASH1 from the Loess Plateau in Yan'an region was collected, and polysaccharides and total flavonoids were extracted, isolated and identified from mycelium and sporophore. In vitro antioxidant activity was detected through the scavenging activity of hydroxy

SUBMITTER: Zhu X 

PROVIDER: S-EPMC10166811 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature