Prognostic nomogram for multiple myeloma early relapse after autologous stem cell transplant in the novel agent era.

ABSTRACT:

Background

The present study intended to establish a predictive nomogram for early relapse (ER) (<12 months) after autologous stem cell transplantation (ASCT) in the novel drug era for multiple myeloma (MM).

Patients and methods

The nomogram was designed and constructed to a retrospective clinical data of newly diagnosed MM patients received novel agent induction therapy and subsequent ASCT at three centers in China from July 2007 to December 2018. The retrospective study was conducted among 294 patients in the training cohort and 126 in the validation cohort. The nomogram's predictive accuracy was evaluated by the concordance index, calibration curve and decision clinical curve.

Results

The study cohort included 420 newly diagnosed MM patients, and 100 (23.8%) were i

SUBMITTER: Zhou H 

PROVIDER: S-EPMC10166899 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature