Automated oxygen control for very preterm infants and neurodevelopmental outcome at 2 years-a retrospective cohort study.

ABSTRACT: Faster resolution of hypoxaemic or hyperoxaemic events in preterm infants may reduce long-term neurodevelopmental impairment. Automatic titration of inspiratory oxygen increases time within the oxygen saturation target range and may provide a more prompt response to hypoxic and hyperoxic events. We assessed routinely performed follow-up at 2 years of age after the implementation of automated oxygen control (AOC) as standard care and compared this with a historical cohort. Neurodevelopmental outcomes at 2 years of age were compared for infants born at 24-29 weeks gestational age before (2012-2015) and after (2015-2018) the implementation of AOC as standard of care. The primary outcome was a composite outcome of either mortality or severe neurodevelopmental impairment (NDI), and other outcom

SUBMITTER: Salverda HH 

PROVIDER: S-EPMC10167103 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature