Surgical revascularizations for pediatric moyamoya: a systematic review, meta-analysis, and meta-regression analysis.

ABSTRACT:

Introduction

There is no clear consensus regarding the technique of surgical revascularization for moyamoya disease and syndrome (MMD/MMS) in the pediatric population. Previous meta-analyses have attempted to address this gap in literature but with methodological limitations that affect the reliability of their pooled estimates. This meta-analysis aimed to report an accurate and transparent comparison between studies of indirect (IB), direct (DB), and combined bypasses (CB) in pediatric patients with MMD/MMS.

Methods

In accordance with PRISMA guidelines, systematic searches of Medline, Embase, and Cochrane Central were undertaken from database inception to 7 October 2022. Perioperative adverse events were the primary outcome measure. Secondary outcomes were rates of long-ter

SUBMITTER: Lee KS 

PROVIDER: S-EPMC10167165 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature