Achromatic and chromatic contrast discrimination in patients with type 2 diabetes.

ABSTRACT: Effects of type 2 diabetes on achromatic and chromatic contrast sensitivity (CS) are still controversial. In this study, we aimed to investigate CS in patients without diabetic retinopathy (no-DR) and in those with non-proliferative DR (NPDR) and proliferative DR (PDR) using psychophysical methods with transient and sustained achromatic stimuli and color patches. Achromatic CS was measured with the pulsed pedestal (PP) paradigm (7, 12, and 19 cd/m²) and pedestal-△-pedestal (P-△-P) paradigm (11.4, 18, and 28.5 cd/m²). A chromatic discrimination paradigm that assesses protan, deutan, and tritan color vision was adopted. Forty-two patients (no-DR n = 24, NPDR n = 12, PDR = 6; male n = 22, mean age = 58.1 y/o) and 38 controls (male n = 18, mean age = 53.4 y/o) participate

SUBMITTER: Tsai LT 

PROVIDER: S-EPMC10167204 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature