Ex vivo magnetic resonance elastography of the small bowel in Crohn's disease.

ABSTRACT:

Background

Conventional magnetic resonance enterography is limited in differentiating active inflammation and fibrosis in lesions of Crohn's disease (CD), thus providing a restricted basis for therapeutic decision making. Magnetic resonance elastography (MRE) is an emerging imaging tool that differentiates soft tissues on the basis of their viscoelastic properties. The aim of this study was to demonstrate the feasibility of MRE in assessing the viscoelastic properties of small bowel samples and quantifying differences in viscoelastic properties between healthy ileum and ileum affected by CD.

Methods

Twelve patients (median age: 48 years) were prospectively enrolled in this study between September 2019 and January 2021. Patients of the study group (n=7) underwent surgery for

SUBMITTER: Loch FN 

PROVIDER: S-EPMC10167436 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature