Validation of an automated technique for quantification of pulmonary perfusion territories using computed tomography angiography.

ABSTRACT:

Background

Computed tomography pulmonary angiography (CTPA) is the primary modality for the detection and diagnosis of pulmonary embolism (PE) while the stratification of PE severity remains challenging using angiography. Hence, an automated minimum-cost path (MCP) technique was validated to quantify the subtended lung tissue distal to emboli using CTPA.

Methods

A Swan-Ganz catheter was placed in the pulmonary artery of seven swine (body weight: 42.6±9.6 kg) to produce different PE severities. A total of 33 embolic conditions were generated, where the PE location was adjusted under fluoroscopic guidance. Each PE was induced by balloon inflation followed by computed tomography (CT) pulmonary angiography and dynamic CT perfusion scans using a 320-slice CT scanner. Following im

SUBMITTER: Zhao Y 

PROVIDER: S-EPMC10167474 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature