Why do Older Adults Decline Participation in Research? Results from Two Deprescribing Clinical Trials.

ABSTRACT: Background Heterogenous older adult populations are underrepresented in clinical trials, and their participation is necessary for interventions that directly target them. The purpose of this study was to evaluate reasons why hospitalized older adults declined participation in two deprescribing clinical trials. Methods We report enrollment data from two deprescribing trials, Shed-MEDS (non-Veterans) and VA DROP (Veterans). For both trials, inclusion criteria required participants to be hospitalized, age 50 or older, English-speaking, and taking five or more home medications. Eligible patients were approached for enrollment while hospitalized. When an eligible patient or surrogate declined participation, the reason(s) were recorded and subsequently analyzed inductively to devel

SUBMITTER: Strayer T 

PROVIDER: S-EPMC10168458 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature