Higher consumption of ultra-processed foods and increased likelihood of central nervous system demyelination in a case-control study of Australian adults.

ABSTRACT:

Background

Consumption of ultra-processed foods (UPFs) has been linked to risk of chronic diseases, with scant evidence in relation to multiple sclerosis (MS).

Methods

We tested associations between UPF consumption and likelihood of a first clinical diagnosis of central nervous system demyelination (FCD) (267 cases, 508 controls), a common precursor to MS. We used data from the 2003-2006 Ausimmune Study and logistic regression with full propensity score matching for age, sex, region of residence, education, smoking history, body mass index, physical activity, history of infectious mononucleosis, dietary misreporting, and total energy intake.

Results

Higher UPF consumption was statistically significantly associated with an increased likelihood of FCD (adjusted odds rat

SUBMITTER: Mannino A 

PROVIDER: S-EPMC10169648 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature