Interconnections between urolithiasis and oral health: a cross-sectional and bidirectional Mendelian randomization study.

ABSTRACT:

Introduction

Urolithiasis is one of the most common diseases for urologists and it is a heavy burden for stone formers and society. The theory of the oral-genitourinary axis casts novel light on the pathological process of genitourinary system diseases. Hence, we performed this study to characterize the crosstalk between oral health conditions and urolithiasis to provide evidence for prevention measures and mechanisms of stone formation.

Materials and methods

This population-based cross-sectional study included 86,548 Chinese individuals who had undergone a comprehensive examination in 2017. Urolithiasis was diagnosed depending on the results of ultrasonographic imaging. Logistic models were utilized to characterize the association between oral health conditions and urolithi

SUBMITTER: Xu JZ 

PROVIDER: S-EPMC10169673 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature