Scale-free dynamics in the core-periphery topography and task alignment decline from conscious to unconscious states.

ABSTRACT: Scale-free physiological processes are ubiquitous in the human organism. Resting-state functional MRI studies observed the loss of scale-free dynamics under anesthesia. In contrast, the modulation of scale-free dynamics during task-related activity remains an open question. We investigate scale-free dynamics in the cerebral cortex's unimodal periphery and transmodal core topography in rest and task states during three conscious levels (awake, sedation, and anesthesia) complemented by computational modelling (Stuart-Landau model). The empirical findings demonstrate that the loss of the brain's intrinsic scale-free dynamics in the core-periphery topography during anesthesia, where pink noise transforms into white noise, disrupts the brain's neuronal alignment with the task's temporal structu

SUBMITTER: Klar P 

PROVIDER: S-EPMC10170069 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature