Impact of individual microvascular disease on the risks of macrovascular complications in type 2 diabetes: a nationwide population-based cohort study.

ABSTRACT:

Background

This study compared the risks of cardiovascular morbidity and mortality between patients with type 2 diabetes (T2D) with and without microvascular diseases, and between matched patients with microvascular diseases.

Methods

We identified newly diagnosed type 2 diabetes patients from National Health Insurance Research Database in Taiwan from January 1, 2008, to December 31, 2019. Propensity score matching was applied to construct matched pairs of patients with diabetic kidney disease, retinopathy, or neuropathy. Multivariable Cox proportional-hazard models were adopted to compare the risks of cardiovascular morbidity and mortality.

Results

Patients with microvascular disease had a significantly higher risk of cardiovascular morbidities and mortality than thos

SUBMITTER: Yen FS 

PROVIDER: S-EPMC10170797 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature