Endocervical curettage for diagnosing high-grade squamous intraepithelial lesions or worse in women with type 3 transformation zone lesions: a retrospective, observational study.

ABSTRACT:

Background

This study aimed to assess the value of endocervical curettage (ECC) in detecting high-grade squamous intraepithelial lesion or worse (HSIL+) in women with type 3 transformation zone (TZ3) lesions, and to identify the clinical characteristics of patients with TZ3 lesions who benefit most from ECC.

Methods

This retrospective, multicenter study included 1,905 women with TZ3 lesions who attended cervical screening in one of seven tertiary hospitals in China between January 2020 and November 2021. All participants had received abnormal results and had been referred to colposcopy. Risk factors were identified through univariate and multifactorial logistic analyses.

Results

In total, 20.5% (n = 391) of HSIL+ cases with TZ3 lesions had been diagnosed with biopsy a

SUBMITTER: Wei B 

PROVIDER: S-EPMC10170824 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature