Genetic basis of STEM occupational choice and regional economic performance: a UK biobank genome-wide association study.

ABSTRACT:

Background

Science, technology, engineering, and mathematics (STEM) professionals are regarded as the highly skilled labor force that fosters economic productivity, enterprise innovation, and international competitiveness of a country. This study aims to understand the genetic predisposition to STEM occupations and investigate its associations with regional economic performance. We conducted a genome-wide association study on the occupational choice of STEM jobs based on a sample of 178,976 participants from the UK Biobank database.

Results

We identified two genetic loci significantly associated with participants' STEM job choices: rs10048736 on chromosome 2 and rs12903858 on chromosome 15. The SNP heritability of STEM occupations was estimated to be 4.2%. We also found phen

SUBMITTER: Zhu C 

PROVIDER: S-EPMC10170832 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature