Robust enhancement of motor sequence learning with 4 mA transcranial electric stimulation.

ABSTRACT:

Background and objectives

Motor learning experiments with transcranial direct current stimulation (tDCS) at 2 mA have produced mixed results. We hypothesize that tDCS boosts motor learning provided sufficiently high field intensity on the motor cortex.

Methods

In a single-blinded design, 108 healthy participants received either anodal (N = 36) or cathodal (N = 36) tDCS at 4 mA total, or no stimulation (N = 36) while they practiced a 12-min sequence learning task. Anodal stimulation was delivered across four electrode pairs (1 mA each), with anodes above the right parietal lobe and cathodes above the right frontal lobe. Cathodal stimulation, with reversed polarities, served as an active control for sensation, while the no-stimulation condition established baseline performance

SUBMITTER: Hsu G 

PROVIDER: S-EPMC10171179 | biostudies-literature | 2023 Jan-Feb

REPOSITORIES: biostudies-literature