Mechanical Ventilation in ARDS With an Automatic Resuscitator.

ABSTRACT:

Background

The Oxylator is an automatic resuscitator, powered only by an oxygen cylinder with no electricity required, that could be used in acute respiratory failure in situations in which standard mechanical ventilation is not available or feasible. We aimed to assess the feasibility and safety of mechanical ventilation by using this automatic resuscitator in an animal model of ARDS.

Methods

A randomized experimental study in a porcine ARDS model with 12 pigs randomized to the Oxylator group or the control group (6 per group) and ventilated for 4 h. In the Oxylator group, peak pressure was set at 20 cm H₂O and PEEP was set at the lowest observed breathing frequency during a decremental PEEP titration. The control pigs were ventilated with a conventional ventilat

SUBMITTER: Sousa M 

PROVIDER: S-EPMC10171348 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature