Prefrontal hemodynamics during forward and backward walking, with and without a cognitive task, in people with multiple sclerosis.

ABSTRACT:

Background

Hemodynamics in the prefrontal cortex (PFC) while walking forward and backward, with and without an additional cognitive task (motor single-task [ST] and motor cognitive dual-task [DT]) have not been studied in people with multiple sclerosis (pwMS).

Aim

To investigate the PFC hemodynamics during forward and as well as backward walking, with and without a cognitive task, in pwMS and healthy controls.

Design

Observational case-control study.

Setting

Sheba Multiple Sclerosis Center, Tel-Hashomer, Israel.

Population

Eighteen pwMS (36.1±11.7 years, 66.6% female) and 17 healthy controls (37.5±13.8 years, 76.5% female).

Methods

Each subject completed four walking trials: ST forward walking, DT forward walking, ST backward walking, DT backward

SUBMITTER: Kupchenko Y 

PROVIDER: S-EPMC10171363 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature