Therapeutic potential of tumor treating fields for malignant brain tumors.

ABSTRACT:

Background

Malignant brain tumors are among the most threatening diseases of the central nervous system, and despite increasingly updated treatments, the prognosis has not been improved. Tumor treating fields (TTFields) are an emerging approach in cancer treatment using intermediate-frequency and low-intensity electric field and can lead to the development of novel therapeutic options.

Recent findings

A series of biological processes induced by TTFields to exert anti-cancer effects have been identified. Recent studies have shown that TTFields can alter the bioelectrical state of macromolecules and organelles involved in cancer biology. Massive alterations in cancer cell proteomics and transcriptomics caused by TTFields were related to cell biological processes as well as mul

SUBMITTER: Zhou Y 

PROVIDER: S-EPMC10172187 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature