Does obstructive sleep apnoea modulate cardiac autonomic function in paroxysmal atrial fibrillation?

ABSTRACT:

Purpose

The autonomic nervous system may mediate acute apnoea-induced atrial fibrillation (AF). We compared cardiac autonomic function in paroxysmal atrial fibrillation (PAF) patients with and without obstructive sleep apnoea (OSA).

Methods

Case control study of 101 patients with PAF recruited at two tertiary centres. All patients underwent in-laboratory polysomnography. ECG signal demonstrating "steady state" sinus rhythm (i.e. with arrhythmic beats and respiratory events excluded) was included in the analysis. Cardiac autonomic function was assessed via measures of heart rate variability (HRV) and reported by sleep stage (REM vs Non-REM) for patients with and without OSA.

Results

Sixty-five (66.3%) of patients were male, mean age 61.5 ± 11.6 years, mean BMI 27.1 ± 4

SUBMITTER: Mohammadieh AM 

PROVIDER: S-EPMC10172286 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature