New insights into the characteristic skin microorganisms in different grades of acne and different acne sites.

ABSTRACT:

Background

The increasing maturity of sequencing technology provides a convenient approach to studying the role of skin microorganisms in acne pathogenesis. However, there are still too few studies about the skin microbiota of Asian acne patients, especially a lack of detailed analysis of the characteristics of the skin microbiota in the different acne sites.

Methods

In this study, a total of 34 college students were recruited and divided into the health, mild acne, and severe acne groups. The bacterial and fungal flora of samples were separately detected by 16S and 18S rRNA gene sequencing. The biomarkers of different acne grades and different acne sites [forehead, cheek, chin, torso (including chest and back)] were excavated.

Results and discussion

Our results indic

SUBMITTER: Guo Z 

PROVIDER: S-EPMC10172595 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature