The Association of Physical Activity Behaviors and Patterns With Aging Acceleration: Evidence From the UK Biobank.

ABSTRACT: Prior evidence suggests that physical activity may reduce the risk of multiple diseases and mortality. However, whether and how physical activity affects the aging process remains largely unexplored. We included 284 479 UK Biobank participants and computed leukocyte telomere length (LTL) deviation (ie, the difference between genetically determined and observed LTL) and biological age acceleration (defined as the discrepancy between the phenotypic age of a person and the average phenotypic age in the cohort of individuals with the same age and sex) as the indexes for aging acceleration. Linear and logistic models were used to estimate the associations of self-reported physical activity items and patterns (identified by principal component analysis), as well as accelerometer-assessed physica

SUBMITTER: Zhu J 

PROVIDER: S-EPMC10172984 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature