Advances in intranasal vaccine delivery: A promising non-invasive route of immunization.

ABSTRACT: The importance of vaccination has been proven particularly significant the last three years, as it is revealed to be the most efficient weapon for the prevention of several infections including SARS-COV-2. Parenteral vaccination is the most applicable method of immunization, for the prevention of systematic and respiratory infections, or central nervous system disorders, involving T and B cells to a whole-body immune response. However, the mucosal vaccines, such as nasal vaccines, can additionally activate the immune cells localized on the mucosal tissue of the upper and lower respiratory tract. This dual stimulation of the immune system, along with their needle-free administration favors the development of novel nasal vaccines to produce long-lasting immunity. In recent years, the nanopar

SUBMITTER: Kehagia E 

PROVIDER: S-EPMC10173027 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature