Cellulose Nanofiber Platform for Pesticide Sequestration in the Gastrointestinal Tract.

ABSTRACT: Exploitation of nature-derived materials is an important approach to promote environmental sustainability. Among these materials, cellulose is of particular interest due to its abundance and relative ease of access. As a food ingredient, cellulose nanofibers (CNFs) have found interesting applications as emulsifiers and modulators of lipid digestion and absorption. In this report, we show that CNFs can also be modified to modulate the bioavailability of toxins, such as pesticides, in the gastrointestinal tract (GIT) by forming inclusion complexes and promoting interaction with surface hydroxyl groups. CNFs were successfully functionalized with (2-hydroxypropyl)-β-cyclodextrin (HPBCD) using citric acid as a crosslinker via esterification. Functionally, the potential for pristine and function

SUBMITTER: Ho CG 

PROVIDER: S-EPMC10173348 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature