COVID-19 testing protocols to guide duration of isolation: a cost-effectiveness analysis.

ABSTRACT:

Background

The Omicron variant of SARS-CoV-2 led to a steep rise in transmissions, and emerging variants continue to influence case rates across the US. As public tolerance for isolation abated, CDC guidance on duration of at-home isolation of COVID-19 cases was shortened to five days if no symptoms, with no laboratory test requirement, despite more cautious approaches advocated by other federal experts.

Methods

We conducted a decision tree analysis of alternative protocols for ending COVID-19 isolation, estimating net costs (direct and productivity), secondary infections, and incremental cost-effectiveness ratios. Sensitivity analyses assessed the impact of input uncertainty.

Results

Per 100 individuals, five-day isolation had 23 predicted secondary infections and a

SUBMITTER: Maya S 

PROVIDER: S-EPMC10173903 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature