Prevalence and global trends of polypharmacy in patients with chronic liver disease: A systematic review and meta-analysis.

ABSTRACT:

Background

Despite its central role in drug metabolism, the exact prevalence estimates and factors affecting global trends of polypharmacy in patients with chronic liver disease (CLD) have remained unexamined. The aim of this systematic review and meta-analysis is to estimate the prevalence of polypharmacy in patients with CLD and to comprehensively synthesize the socio-demographic factors that drive this.

Methods

We conducted a comprehensive search of relevant databases (PubMed, EMBASE, Science citation index, Cochrane Database of Systematic Reviews, and database of abstracts of reviews of effectiveness) for studies published from inception to May 30, 2022 that reported on prevalence estimates of polypharmacy in patients with CLD. The risk of bias was conducted utilizing Lo

SUBMITTER: Danjuma MI 

PROVIDER: S-EPMC10174406 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature