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Understanding West Nile virus transmission: Mathematical modelling to quantify the most critical parameters to predict infection dynamics.


ABSTRACT: West Nile disease is a vector-borne disease caused by West Nile virus (WNV), involving mosquitoes as vectors and birds as maintenance hosts. Humans and other mammals can be infected via mosquito bites, developing symptoms ranging from mild fever to severe neurological infection. Due to the worldwide spread of WNV, human infection risk is high in several countries. Nevertheless, there are still several knowledge gaps regarding WNV dynamics. Several aspects of transmission taking place between birds and mosquitoes, such as the length of the infectious period in birds or mosquito biting rates, are still not fully understood, and precise quantitative estimates are still lacking for the European species involved. This lack of knowledge affects the precision of parameter values when modelling th

SUBMITTER: Fesce E 

PROVIDER: S-EPMC10174579 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature