Interplay between external inputs and recurrent dynamics during movement preparation and execution in a network model of motor cortex.

ABSTRACT: The primary motor cortex has been shown to coordinate movement preparation and execution through computations in approximately orthogonal subspaces. The underlying network mechanisms, and the roles played by external and recurrent connectivity, are central open questions that need to be answered to understand the neural substrates of motor control. We develop a recurrent neural network model that recapitulates the temporal evolution of neuronal activity recorded from the primary motor cortex of a macaque monkey during an instructed delayed-reach task. In particular, it reproduces the observed dynamic patterns of covariation between neural activity and the direction of motion. We explore the hypothesis that the observed dynamics emerges from a synaptic connectivity structure that depends on

SUBMITTER: Bachschmid-Romano L 

PROVIDER: S-EPMC10174693 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature