CT-based three-dimensional invasiveness analysis of adenocarcinoma presenting as pure ground-glass nodules.

ABSTRACT:

Background

We invest computed tomography (CT) image differences between non-invasive adenocarcinomas (NIAs) and invasive adenocarcinomas (IAs) presenting as pure ground glass nodules (GGNs).

Methods

From 2013 to 2019, 48 pure GGNs were surgically resected in 45 patients. Of these, 40 were pathologically diagnosed as non-small cell lung cancers (NSCLCs). We assessed them using the Synapse Vincent (Fujifilm Co., Ltd., Tokyo, Japan) three-dimensional (3D) analysis system; we drew histograms of the CT densities. We calculated the maximum, minimum, means, and standard deviations of the densities. The proportions of GGNs of high CT density were compared between the two groups. The diagnostic performance was investigated via receiver operating curve (ROC) analysis.

Results

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SUBMITTER: Oh J 

PROVIDER: S-EPMC10174765 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature