Cholesterol and breast cancer risk: a cohort study using health insurance claims and health checkup databases.

ABSTRACT:

Purpose

This study aimed to investigate the association between serum cholesterol and triglyceride levels and breast cancer risk in Japanese women.

Methods

We retrospectively evaluated the association between the levels of low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and triglycerides (TGs) and the incidence of breast cancer in a cohort study by using the health insurance claims and health checkup data from a database provided by JMDC Inc. We included 956,390 women who were insured between April 2008 and June 2019, identified breast cancer cases by using validated definitions, and estimated the risk of breast cancer by using multivariable Cox proportional hazards regression models adjusted for potential confounders.

Results

SUBMITTER: Narii N 

PROVIDER: S-EPMC10175375 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature