The risk of central nodal metastasis based on prognostic factors of the differentiated thyroid carcinoma: a systematic review and meta-analysis study.

ABSTRACT:

Background and aim

Despite improving the 10-year disease-free-survival, prophylactic central neck dissection (pCND) in differentiated thyroid carcinoma (DTC) should only be considered in patients with high risk factors for lymph node (LN) metastasis due to the increases in the risk of postoperative complications. Our aim was to identify the risk factors for central lymph node metastasis (CLNM) in DTC.

Method

We searched PubMed, Scopus, Web of science, Cochrane library for eligible studies from inception to November 1, 2021 and a systematic review and meta-analysis were carried out to identify the risk factors for CLNM in DTC.

Results

We included 41 studies with total of 27,741 patients in this study. The pooled results in this meta-analysis showed that these risk fact

SUBMITTER: Hafez LG 

PROVIDER: S-EPMC10175472 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature