Corticosteroid outcome may be dependent of duration of use in severe COVID-19.

ABSTRACT:

Background/aims

For patients hospitalized with coronavirus disease 2019 (COVID-19) who require supplemental oxygen, the evidence of the optimal duration of corticosteroid is limited. This study aims to identify whether long-term use of corticosteroids is associated with decreased mortality.

Methods

Between February 10, 2020 and October 31, 2021, we analyzed consecutive hospitalized patients with COVID-19 with severe hypoxemia. The patients were divided into short-term (≤ 14 days) and long-term (> 14 days) corticosteroid users. The primary outcome was 60-day mortality. We performed propensity score (PS) analysis to mitigate the effect of confounders and conducted Kaplan-Meier curve analysis.

Results

There were 141 (52%) short-term users and 130 (48%) long-term corticos

SUBMITTER: Kim JH 

PROVIDER: S-EPMC10175872 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature