Fluorescence guidance improves the accuracy of radiological imaging-guided surgical navigation.

ABSTRACT:

Background

Imaging-based navigation technologies require static referencing between the target anatomy and the optical sensors. Imaging-based navigation is therefore well suited to operations involving bony anatomy; however, these technologies have not translated to soft-tissue surgery. We sought to determine if fluorescence imaging complement conventional, radiological imaging-based navigation to guide the dissection of soft-tissue phantom tumors.

Methods

Using a human tissue-simulating model, we created tumor phantoms with physiologically accurate optical density and contrast concentrations. Phantoms were dissected using all possible combinations of computed tomography (CT), magnetic resonance, and fluorescence imaging; controls were included. The data were margin accuracy

SUBMITTER: Henderson ER 

PROVIDER: S-EPMC10176708 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature