Combined Pulmonary Fibrosis and Emphysema: When Scylla and Charybdis Ally.

ABSTRACT: Combined pulmonary fibrosis and emphysema (CPFE) is a recently recognized syndrome that, as its name indicates, involves the existence of both interstitial lung fibrosis and emphysema in one individual, and is often accompanied by pulmonary hypertension. This debilitating, progressive condition is most often encountered in males with an extensive smoking history, and is presented by dyspnea, preserved lung volumes, and contrastingly impaired gas exchange capacity. The diagnosis of the disease is based on computed tomography imaging, demonstrating the coexistence of emphysema and interstitial fibrosis in the lungs, which might be of various types and extents, in different areas of the lung and several relative positions to each other. CPFE bears high mortality and to date, specific and effi

SUBMITTER: Gredic M 

PROVIDER: S-EPMC10177208 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature